Relationship Between Metabolic Syndrome and Non-Dipping Blood Pressure Pattern in Obese Patient

Background: Metabolic syndrome and non-dipping blood pressure pattern are related with cardiovascular disease. It is considered that there may be common pathophysiological mechanisms of these clinical entities. We aimed to investigate the association between metabolic syndrome and nondipping blood pressure pattern. Method: 118 consecutive newly diagnosed metabolic syndrome patients with obesity who underwent 24-hour ambulatory blood pressure monitoring were included in the study. They were divided into dipper n = 46 and non-dipper n = 72 groups. Nocturnal non-dipping blood pressure pattern is defined as the lower than 10 % reduction in nocturnal mean systolic and/or diastolic blood pressure. Results: In the whole population, mean 24-hour ambulatory blood pressure was 146/96 mmHg. Although, the two groups was similar in terms of basic characteristics; the frequency of metabolic syndrome was significantly greater in patients with non-dipping pattern p=0.038 . Conclusion: In this study metabolic syndrome was found to be more prevalent among patients with non-dipping pattern of hypertension. This may indicate a common pathophysiologic mechanism of metabolic syndrome and non-dipping blood pressure pattern in obese patient