Key result
Metabolic syndrome was associated with a significantly higher prevalence of a nondipper blood pressure profile compared to patients without metabolic syndrome (46.1% vs 37.5%, P<0.001).
Why the study?
Is metabolic syndrome associated with a nondipping blood pressure profile in untreated hypertensive patients?
Population
1,770 nondiabetic, untreated hypertensive patients (824 men and 946 women), mean age 48.7 +/- 13.2 years.
Comparison
Presence of metabolic syndrome (MS) vs Absence of metabolic syndrome
Design
Cross-sectional
Follow-up
48 hours
Authors
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May link metabolic syndrome to nondipping in untreated hypertensives; leaves open causal role and need for prospective confirmation.
Cross-Sectional (n=1,770)
Is metabolic syndrome associated with a nondipping blood pressure profile in untreated hypertensive patients?
Absolute Event Rate: 46.1% vs 37.5%
p-value: p=<0.001
Metabolic syndrome is significantly associated with a blunted nocturnal blood pressure decline (nondipping) and elevated cardiovascular risk markers in untreated hypertensive patients.
Hermida et al. (2009) conducted a cross-sectional in Untreated hypertension (n=1,770). Metabolic syndrome vs. Absence of metabolic syndrome was evaluated on Nondipper blood pressure profile (<10% decline in asleep relative to awake BP mean) (p=<0.001). Metabolic syndrome was associated with a significantly higher prevalence of a nondipper blood pressure profile compared to patients without metabolic syndrome (46.1% vs 37.5%, P<0.001).
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