Key result
Metabolic syndrome was associated with a higher prevalence of an altered non-dipper blood pressure profile compared to patients without metabolic syndrome (48.4% vs 36.1%, p<0.001).
Why the study?
Does the presence of metabolic syndrome alter the circadian ambulatory blood pressure pattern in untreated hypertensive patients?
Population
2,045 non-diabetic untreated patients with uncomplicated essential hypertension, mean age 48.7+/-11.9 years
Comparison
Presence of metabolic syndrome (MS) vs Absence of metabolic syndrome (MS)
Design
Cross-sectional
Follow-up
48 consecutive hours
Authors
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Non-dipping BP patterns may warrant closer ambulatory monitoring in metabolic syndrome; leaves open whether targeting circadian BP improves outcomes.
Cross-Sectional (n=2,045)
Does the presence of metabolic syndrome alter the circadian ambulatory blood pressure pattern in untreated hypertensive patients?
Absolute Event Rate: 48.4% vs 36.1%
p-value: p=<0.001
Ayala et al. (2009) conducted a cross-sectional in Uncomplicated essential hypertension (n=2,045). Metabolic syndrome vs. Without metabolic syndrome was evaluated on Prevalence of an altered non-dipper blood pressure profile (p=<0.001). Metabolic syndrome was associated with a higher prevalence of an altered non-dipper blood pressure profile compared to patients without metabolic syndrome (48.4% vs 36.1%, p<0.001).
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