Key result
Slow infusion of epinephrine increased left ventricular distensibility in dogs, producing large changes in ventricular performance at a given filling pressure.
Authors
Loading...
Hypothesis-generating in canine models; leaves open translation to human HF management and should not change practice.
Hefner et al. (1961) studied this question. Epinephrine infusion, hemorrhage, and blood transfusion vs. Control circumstances (baseline) was evaluated on Left ventricular diastolic pressure-circumference curves (distensibility). Slow infusion of epinephrine increased left ventricular distensibility in dogs, producing large changes in ventricular performance at a given filling pressure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: