Key result
Reported family history of myocardial infarction had modest sensitivity (67.3% in cases, 68.5% in controls), with recall bias for siblings' histories (reported OR 1.67; 95% CI 1.09-2.57).
Why the study?
Is reported family history of myocardial infarction reliable compared to validated records in men with and without prior myocardial infarction?
Case-Control (n=400)
No
Is reported family history of myocardial infarction reliable compared to validated records in men with and without prior myocardial infarction?
Absolute Event Rate: 67.3% vs 68.5%
Reported family history of myocardial infarction has modest sensitivity and positive predictive value, limiting its utility as a standalone tool for targeted screening.
Authors
No takes yet. Share an insight, caveat, or question.
Limits reliance on reported family history alone for MI screening; leaves open whether validated records improve risk models.
Kee et al. (1993) conducted a case-control in Myocardial infarction (n=400). Reported family history of myocardial infarction vs. Validated family history from medical records was evaluated on Sensitivity of reported family histories of myocardial infarction. Reported family history of myocardial infarction had modest sensitivity (67.3% in cases, 68.5% in controls), with recall bias for siblings' histories (reported OR 1.67; 95% CI 1.09-2.57).
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: