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May 1, 1952American Journal of Epidemiology

Multiplication of Poliomyelitis Viruses in Tissue Cultures of Monkey Testes:

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Key result

The study describes the growth curves of Type 1 (Brunhilde) and Type 2 (Lansing) poliomyelitis virus strains in monkey testes tissue cultures and a quantitative neutralization test.

Population

Tissue cultures of monkey testes

Design

Preclinical

Authors

NLNada LedinkoBennington CollegeJRJohn T. RiordanHope CollegeJMJoseph L. MelnickStatens Serum Institut

Discussion

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Implication

Monkey tissue culture data remain preliminary; leaves open translation to human polio neutralization assays.

Structured PICO

P
Population
Tissue cultures of monkey testes
I
Intervention
Poliomyelitis viruses Type 1 (Brunhilde) and Type 2 (Lansing) strains
O
Outcome
Growth curves and quantitative neutralization test

Cite This Study

Ledinko et al. (1952) studied Poliomyelitis. Tissue cultures of monkey testes was evaluated. The study describes the growth curves of Type 1 (Brunhilde) and Type 2 (Lansing) poliomyelitis virus strains in monkey testes tissue cultures and a quantitative neutralization test.

synapsesocial.com/papers/6a0cd04163ecdfd686625810https://doi.org/10.1093/oxfordjournals.aje.a119524
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1STUDIES ON POLIOMYELITIS VIRUSES IN CULTURES OF MONKEY TESTICULAR TISSUE11952 · 21 citations
  2. 2STUDIES ON POLIOMYELITIS VIRUSES IN CULTURES OF MONKEY TESTICULAR TISSUE121952 · 11 citations
  3. 3STUDIES ON THE CULTIVATION OF POLIOMYELITIS VIRUSES IN TISSUE CULTURE1951 · 78 citations
  4. 4DIFFERENTIATION OF TYPES OF POLIOMYELITIS VIRUSES1949 · 56 citations
  5. 5SURVIVAL AND MULTIPLICATION OF THE VIRUS OF POLIOMYELITIS IN VITRO1930 · 13 citations