Left ventricular activation time and pattern are preserved with both selective and nonselective His bundle pacing
Key result
nsHBP preserves LV activation time and pattern versus sHBP despite early basal RV activation.
- P=.108
Why the study?
The impact of ventricular pre-excitation during nonselective His bundle pacing on left and right ventricular dyssynchrony was unknown.
Does nonselective His bundle pacing alter left and right ventricular activation time and pattern compared to selective His bundle pacing in patients displaying both?
Population
Patients who displayed both S-HBP and NS-HBP
Comparison
S-HBP vs NS-HBP
Design
Noninvasive epicardial electrical mapping study
Authors
Discussion
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Member takes
Implication
Supports equivalence of nonselective and selective His bundle pacing for LV synchrony; leaves open effects on clinical outcomes.
Study Design
Type
Observational
Structured PICO
Does nonselective His bundle pacing alter left and right ventricular activation time and pattern compared to selective His bundle pacing in patients displaying both?
P
Population
Patients who displayed both selective His bundle pacing (S-HBP) and nonselective His bundle pacing (NS-HBP)
I
Intervention
Nonselective His bundle pacing (NS-HBP)
C
Comparator
Selective His bundle pacing (S-HBP)
O
Outcome
Left and right ventricular activation time (LVAT and RVAT) and pattern assessed via noninvasive epicardial electrical mappingsurrogate
Main Result
p-value: p=.108
Nonselective His bundle pacing preserves left ventricular activation time and pattern compared to selective His bundle pacing, suggesting left ventricular dyssynchrony is not a major factor when choosing between the two modalities.
Cite This Study
Arnold et al. (2021) conducted an observational in Patients displaying both S-HBP and NS-HBP. Nonselective His bundle pacing (NS-HBP) vs. Selective His bundle pacing (S-HBP) was evaluated on Left and right ventricular activation time (LVAT and RVAT) and pattern (p=.108). Nonselective His bundle pacing preserves left ventricular activation time and pattern compared to selective His bundle pacing, despite producing early basal right ventricular activation.