Key result
Prophylactic parenteral cephaloridine (n=376) significantly reduced the rate of wound infection across most types of general surgical operations compared to untreated controls (n=386).
Why the study?
Does prophylactic parenteral cephaloridine reduce the rate of wound infection in general surgical wounds?
RCT (n=762)
random
Does prophylactic parenteral cephaloridine reduce the rate of wound infection in general surgical wounds?
Three parenteral doses of prophylactic cephaloridine significantly reduce the rate of surgical wound infections in most general surgical procedures.
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Supports prophylactic cephaloridine in general surgery; confirms perioperative antibiotic efficacy in reducing wound infections.
Evans et al. (1973) conducted an RCT in general surgical wounds (n=762). cephaloridine vs. untreated controls was evaluated on wound infection. Prophylactic parenteral cephaloridine (n=376) significantly reduced the rate of wound infection across most types of general surgical operations compared to untreated controls (n=386).
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