Key result
DC shock treatment converted 87% of atrial fibrillation patients to sinus rhythm, with 13.4% maintaining sinus rhythm at 12 months; quinidine pretreatment did not significantly improve late results.
Why the study?
Does pretreatment with quinidine improve the persistence of sinus rhythm after DC shock treatment in patients with atrial fibrillation?
Population
164 patients with atrial fibrillation
Comparison
DC shock treatment with quinidine pretreatment vs Controls
Design
Cohort
Follow-up
12 months
Authors
Loading...
1-year sinus rhythm maintenance after DC cardioversion in AF is low and unaffected by quinidine; leaves open better strategies for rhythm control.
Cohort (n=164)
Does pretreatment with quinidine improve the persistence of sinus rhythm after DC shock treatment in patients with atrial fibrillation?
Long-term persistence of sinus rhythm after DC cardioversion for atrial fibrillation is low and is not improved by quinidine pretreatment, though shorter AF duration, younger age, normal heart size, and specific etiologies favor better outcomes.
Waris et al. (1971) conducted a cohort in Atrial fibrillation (n=164). DC shock treatment with or without quinidine pretreatment vs. Controls (no quinidine pretreatment) was evaluated on Persistence of sinus rhythm at 12 months. DC shock treatment converted 87% of atrial fibrillation patients to sinus rhythm, with 13.4% maintaining sinus rhythm at 12 months; quinidine pretreatment did not significantly improve late results.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: