Key result
Modern STEMI reperfusion therapy cuts early mortality to ~4%.
Why the study?
Does reperfusion therapy reduce early mortality in patients with STEMI?
Does reperfusion therapy reduce early mortality in patients with STEMI?
The evolution of reperfusion therapy, culminating in primary PCI as the treatment of choice, has dramatically reduced early mortality in STEMI patients.
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Supports reperfusion as STEMI standard of care; leaves open further mortality reductions via contemporary trials.
Frans Van de Werf (2014) conducted a review in ST-segment-elevation myocardial infarction (STEMI). Coronary reperfusion (primary PCI and thrombolysis) was evaluated. Reperfusion therapy for STEMI, including primary PCI and thrombolysis, has reduced early mortality from 16-18% historically to approximately 4% in modern randomized trials.
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