Electro-echocardiographic Indices to Predict Cardiac Resynchronization Therapy Non-response on Non-ischemic Cardiomyopathy

Figures

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  Figure 1. Indicated the difference of related UCG parameters between CRT responders and CRT non-responders. All bars in white color referred to CRT responders, while bars in black color represented for CRT non-responders. Besides, all of the p values here were less than 0.001 (CRT responders vs CRT non-responders).

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  Figure 2. Showed ROC curve to predict the optimal cut off of CRT non-response predictors, and all p values were less than 0.01. The optimal cut-off point was in the upper-left area and was calculated based on the maximal Youden index (sensitivity + specificity − 1). (A) Was ROC curve of LAV; (B) was ROC curve of LVESV; (C) was ROC curve of LVEDV; (D) was ROC curve of S wave; (E) was ROC curve of QRS duration; (F) was ROC curve of TpTe/QTc.

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  Figure 3. Showed univariate logistic regression analysis of electro-echocardiographic indices and other clinical factors for predicting CRT non-response. Odds ratio (OR) and its 95% credential interval (CI) of each factor was presented as point and line respectively. Risk of CTR non-response increased when OR > 1, while it decreased when OR < 1. HF = heart failure; NYHA = New York Heart Association; AF = atrial fibrillation; HTN = hypertension; DM = diabetes mellitus; AV = left atrial volume; SV = left ventricular end systolic volume; DV = left ventricular end diastolic volume; CLBBB = complete left bundle branch block.

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  Figure 4. Was the comparison of electrocardiographic indice about dispersion of repolarization between pre-CRT placement and post-CRT placement. (A) and (B) showed QT interval, TpTe and TpTe/QTc significantly increased within 3 days after CRT implantation indicating CRT prompting TDR increasing in early stage (white bars represented for indices of pre-CRT, and black bars referred to indices of post-CRT).

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  Figure 5. Showed difference of Scr level between CRT responders and CRT non-responders after 1 year. Bar in white color referred to CRT responders, while bar in black color represented for CRT non-responders.