Why the study?
Does adequacy of left ventricular contraction determine survival after coronary artery bypass surgery in patients undergoing myocardial revascularization?
Does adequacy of left ventricular contraction determine survival after coronary artery bypass surgery in patients undergoing myocardial revascularization?
Adequacy of left ventricular contraction, primarily an ejection fraction above 40%, is the major determinant of surgical survival in patients undergoing coronary artery bypass surgery.
EF >40% associated with post-CABG survival; hypothesis-generating for risk stratification, needs prospective validation.
Review of our first 180 consecutive patients undergoing myocardial revascularization surgery at the Peter Bent Brigham Hospital shows that the over-all surgical mortality was 5.5%. Mortality in patients not in shock at the time of operation was 2.3%. The only major determinant of surgical survival appeared to be adequacy of left ventricular contraction, as indicated primarily by an ejection fraction above 40%. Of 116 patients operated on for relief of chronic angina pectoris or the intermediate coronary syndrome, 71% were free of angina 6 to 24 months (average 8.9) after surgery. The aggregate operative and late mortality in this group during the period of follow-up was 4.3%.
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Collins et al. (1973) studied this question.
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