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January 1, 2013Journal of Cardiovascular Magnetic ResonanceOpen Access

Moderate intensity supine exercise in healthy volunteers decreased total heart volume by 4% and increased total heart volume variation from 5.9% to 9.7%.

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Why the study?

Does moderate intensity supine exercise alter cardiac volumes and pumping mechanisms in healthy volunteers?

Population

26 healthy volunteers (6 women), mean age 30±8 years (range 19-59), with no signs of cardiac disease.

Comparison

Moderate intensity supine exercise using… vs Resting state.

Design

Other

Key result

Moderate intensity supine exercise in healthy volunteers decreased total heart volume by 4% and increased total heart volume variation from 5.9% to 9.7%.

Authors

KSKatarina Steding‐EhrenborgRJRobert JablonowskiPAPer M. Arvidsson

Discussion

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Overview

May alter supine exercise CMR volume interpretation in health; leaves open effects in cardiovascular disease.

Study Design

Type

Observational (n=26)

Multicenter

No

Structured PICO

Does moderate intensity supine exercise alter cardiac volumes and pumping mechanisms in healthy volunteers?

P
Population
26 healthy volunteers (6 women), mean age 30±8 years (range 19-59), with no signs of cardiac disease.
I
Intervention
Moderate intensity supine exercise using one-legged knee extensions on a custom-built MR-compatible ergometer, targeting a heart rate approximately 40 bpm higher than resting.
C
Comparator
Resting state (baseline measurements prior to exercise).
O
Outcome
Changes in left ventricular (LV), right ventricular (RV), and total heart volumes (THV), as well as cardiac pumping mechanisms (longitudinal and radial contribution to stroke volume) measured by cardiovascular magnetic resonance (CMR).surrogate

Main Result

Absolute Event Rate: 9.7% vs 5.9%

p-value: p=<0.001

Moderate intensity supine exercise decreases total heart volume due to reduced right ventricular volume, while increasing radial pumping contribution to stroke volume.

Limitations

  • Exercise heart rate only increased by approximately 40 bpm over resting HR
  • Small subpopulation (n=6) for reproducibility tests
  • Performed in the supine position, limiting interpretation to supine exercise or microgravity
  • Small subpopulation for reproducibility analysis (n=6)
  • Performed in supine position, limiting interpretation to supine exercise or microgravity
  • Relatively low exercise heart rate (+40 bpm over resting)

Cite This Study

Steding‐Ehrenborg et al. (2013) conducted an observational in Healthy volunteers (n=26). Moderate intensity supine exercise vs. Rest was evaluated on Total heart volume variation (THVV) (p=<0.001). Moderate intensity supine exercise in healthy volunteers decreased total heart volume by 4% and increased total heart volume variation from 5.9% to 9.7%.

synapsesocial.com/papers/6a10ef9669716c70d0488ffahttps://doi.org/10.1186/1532-429x-15-96
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