Key result
Cardiac CT data reconstruction with a slice thickness of 0.9 mm at 5% RR-interval achieved 87.0% diagnostic accuracy for predicting elevated filling pressure, significantly higher than reconstructions with 3 mm slice thickness.
Why the study?
Does cardiac CT with specific reconstruction parameters accurately estimate diastolic filling pressure compared to echocardiography?
Cross-Sectional (n=46)
Single-blind
No
Does cardiac CT with specific reconstruction parameters accurately estimate diastolic filling pressure compared to echocardiography?
Cardiac CT reconstructed with thin slices (0.9 mm) and frequent sampling (5% RR-interval) optimizes the estimation of diastolic filling pressure compared to echocardiography.
Answers are grounded in this paper and cite their sources.
Optimized thin-slice CT reconstruction may aid noninvasive filling pressure estimation; leaves open prospective validation versus echocardiography.
Objective: To determine the optimal CT image reconstruction parameters for the measurement of early transmitral peak velocity (E), early peak mitral septal tissue velocity (E'), and E / E' . Materials and Methods: Forty-six patients underwent simultaneous cardiac CT and echocardiography on the same day. Four CT datasets were reconstructed with a slice thickness/interval of 0.9/0.9 mm or 3/3 mm at 10 (10% RR-interval) or 20 (5% RRinterval) RR-intervals. The E was calculated by dividing the peak transmitral flow (mL/s) by the corresponding mitral valve area (cm 2 ). E' was calculated from the changes in the left ventricular length per cardiac phase. E / E' was then estimated and compared with that from echocardiography. Results: For assessment of E / E', CT and echocardiography were more strongly correlated (p < 0.05) with a slice thickness of 0.9 mm and 5% RR-interval (r = 0.77) than with 3 mm or 10% RR-interval. The diagnostic accuracy of predicting elevated filling pressure (E / E' 13, n = 14) was better with a slice thickness of 0.9 mm and 5% RR-interval (87.0%) than with 0.9 mm and 10% RR-interval (71.7%) (p = 0.123) and significantly higher than that with a slice thickness of 3 mm with 5% (67.4%) and 10% RR-interval (63.0%), (p < 0.05), respectively. Conclusion: Data reconstruction with a slice thickness of 0.9 mm at 5% RR-interval is superior to that with a slice thickness of 3 mm or 10% RR-interval in terms of the correlation of E / E' between CT and echocardiography. Thin slices and frequent sampling also allow for more accurate prediction of elevated filling pressure.
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Hwang et al. (2017) conducted a cross-sectional in Suspected coronary artery disease (n=46). Cardiac CT (0.9 mm slice thickness, 5% RR-interval) vs. Cardiac CT (3 mm slice thickness, 10% RR-interval) was evaluated on Diagnostic accuracy for predicting elevated filling pressure (E/E' ≥ 13) (p=<0.05). Cardiac CT data reconstruction with a slice thickness of 0.9 mm at 5% RR-interval achieved 87.0% diagnostic accuracy for predicting elevated filling pressure, significantly higher than reconstructions with 3 mm slice thickness.
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