What does this research mean for the field?

L-nor-epinephrine is an effective pressor agent for the successful treatment of shock accompanying acute myocardial infarction and peripheral vascular collapse. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 11, 1952New England Journal of Medicine

The Clinical Use of Nor-Epinephrine in the Treatment of Shock Accompanying Myocardial Infarction and Other Conditions

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Why the study?

Does nor-epinephrine improve shock accompanying acute myocardial infarction?

Population

Patients with shock accompanying acute myocardial infarction and other conditions

Design

Case_series

Authors

GKGeorge S. KurlandBeth Israel Deaconess Medical Center MMMonte MalachSUNY Downstate Health Sciences University

Discussion

Member takes

Implication

Early norepinephrine experiences in MI shock remain hypothesis-generating; leaves open its role pending randomized trials.

Structured PICO

Does nor-epinephrine improve shock accompanying acute myocardial infarction?

Population

Patients with shock accompanying acute myocardial infarction and other conditions (peripheral vascular collapse)

Intervention

L-nor-epinephrine (arterenol, nor-adrenaline)

Outcome

Treatment of shock

This early paper describes initial clinical experiences using nor-epinephrine as a pressor agent for shock accompanying acute myocardial infarction.

Cite This Study

Kurland et al. (1952) studied this question.

synapsesocial.com/papers/6a1551aa5347fbb1739f95f4 https://doi.org/10.1056/nejm195209112471102

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The Clinical Use of Nor-Epinephrine in the Treatment of Shock Accompanying Myocardial Infarction and Other Conditions

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The Clinical Use of Nor-Epinephrine in the Treatment of Shock Accompanying Myocardial Infarction and Other Conditions

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider