Why the study?
Does a single 0.5 mg oral dose of prazosin improve haemodynamics in patients with stable severe congestive cardiac failure?
Population
6 patients with stable severe congestive cardiac failure
Design
Case_series
Authors
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May support acute hemodynamic benefit in severe HF; leaves open efficacy, dosing, and safety in controlled trials.
Does a single 0.5 mg oral dose of prazosin improve haemodynamics in patients with stable severe congestive cardiac failure?
A single 0.5 mg oral dose of prazosin produces significant and potentially beneficial haemodynamic improvements in patients with severe congestive heart failure.
Horowitz et al. (1984) studied this question.
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