Key result
Bisaramil was the most effective among tested antiarrhythmic drugs in suppressing digitalis- or adrenaline-induced triggered ventricular arrhythmias in dog models.
Why the study?
Does bisaramil suppress triggered ventricular arrhythmias in a dog model of digitalis- or adrenaline-induced arrhythmias?
Does bisaramil suppress triggered ventricular arrhythmias in a dog model of digitalis- or adrenaline-induced arrhythmias?
Bisaramil demonstrated superior efficacy compared to standard antiarrhythmic drugs in suppressing triggered ventricular arrhythmias in a canine model.
Authors
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May guide antiarrhythmic development; leaves open translation from canine models to clinical use.
Haruno et al. (1995) studied Triggered ventricular arrhythmias. Bisaramil vs. Disopyramide, lidocaine, flecainide, verapamil was evaluated on Suppression of triggered ventricular arrhythmias. Bisaramil was the most effective among tested antiarrhythmic drugs in suppressing digitalis- or adrenaline-induced triggered ventricular arrhythmias in dog models.
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