Key result
Synthetic peptides derived from conserved regions of the amino-terminal part of VP1 identified nine group-common linear epitopes recognized by sera from patients with enterovirus infections.
Population
Sera from patients with heterotypic immunoglobulin G antibody responses to enterovirus infections
Design
Preclinical
Authors
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May support broad enterovirus serodiagnostics; hypothesis-generating and requires prospective human validation.
Synthetic peptides from conserved regions of enterovirus VP1 may be useful for developing broad-range serological diagnostic tests.
Cello et al. (1993) studied Enterovirus infections. Synthetic peptides in enzyme-linked immunosorbent assays was evaluated on Identification of group-common linear epitopes. Synthetic peptides derived from conserved regions of the amino-terminal part of VP1 identified nine group-common linear epitopes recognized by sera from patients with enterovirus infections.
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