Key result
Long-term systolic blood pressure variability was higher in patients with silent cerebral white matter lesions (16.2 vs 13.7 mm Hg; P=0.047), but lost significance after adjusting for absolute BP.
Why the study?
Is blood pressure variability associated with the presence of silent cerebral white matter lesions in middle-aged asymptomatic essential hypertensives?
Population
43 middle-aged untreated asymptomatic essential hypertensive patients
Design
Cross-sectional
Authors
Loading...
BP variability association with white matter lesions is not independent of absolute BP; leaves open its incremental role in hypertension.
Cross-Sectional (n=43)
Is blood pressure variability associated with the presence of silent cerebral white matter lesions in middle-aged asymptomatic essential hypertensives?
p-value: p=0.047
Long-term systolic blood pressure variability is associated with silent cerebral white matter lesions in essential hypertension, but this relationship is largely driven by absolute blood pressure elevation.
Gómez-Angelats et al. (2004) conducted a cross-sectional in Essential hypertension (n=43). Blood pressure variability was evaluated on Presence of silent cerebral white matter lesions (p=0.047). Long-term systolic blood pressure variability was higher in patients with silent cerebral white matter lesions (16.2 vs 13.7 mm Hg; P=0.047), but lost significance after adjusting for absolute BP.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: