Key result
The presence of silent cerebral white matter lesions in middle-aged hypertensive patients was associated with worse performance on basic attention (digit span forward score 4.86 vs 5.51; P=0.027).
Why the study?
Does the presence of silent cerebral white matter lesions reduce cognitive function in middle-aged essential hypertensive patients?
Population
60 never-treated essential hypertensive patients, aged 50 to 60 years, without clinical evidence of target…
Comparison
Presence of silent cerebral white matter lesions vs Absence of silent cerebral white matter lesions
Design
Cross-sectional
Authors
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May link silent lesions to attention deficits in hypertensives; hypothesis-generating and requires prospective confirmation.
Cross-Sectional (n=60)
Does the presence of silent cerebral white matter lesions reduce cognitive function in middle-aged essential hypertensive patients?
Absolute Event Rate: 4.86% vs 5.51%
p-value: p=0.027
Cristina Sierra (2004) conducted a cross-sectional in Essential hypertension (n=60). Presence of cerebral white matter lesions vs. Absence of cerebral white matter lesions was evaluated on Cognitive function (digit span forward score) (p=0.027). The presence of silent cerebral white matter lesions in middle-aged hypertensive patients was associated with worse performance on basic attention (digit span forward score 4.86 vs 5.51; P=0.027).
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