Why the study?
Older patients with STEMI represent a very high-risk population, but data on the prognostic value of early CMR in this scenario are scarce.
Does early cardiac magnetic resonance improve prognostic prediction of major adverse cardiac events in older patients (>70 years) with STEMI treated with percutaneous intervention?
Population
247 STEMI patients over 70 years of age treated with percutaneous intervention
Comparison
Addition of CMR parameters vs baseline and echocardiographic characteristics alone
Design
Multicenter prospective registry
Follow-up
4.8-year mean
Key result
Adding cardiac magnetic resonance data to baseline and echocardiographic models significantly improved the prediction of major adverse cardiac events in older STEMI patients (C-statistic 0.759 vs 0.685; P<0.001).
Authors
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May aid risk stratification in older STEMI patients; leaves open need for prospective outcome trials.
Cohort (n=247)
Yes
Does early cardiac magnetic resonance improve prognostic prediction of major adverse cardiac events in older patients (>70 years) with STEMI treated with percutaneous intervention?
Effect estimate: C-statistic 0.759 (95% CI 0.694-0.824)
p-value: p=<0.001
Early cardiac magnetic resonance provides valuable prognostic information that significantly improves the prediction of major adverse cardiac events in older patients with STEMI.
Gabaldon-Perez et al. (2022) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=247). Cardiac magnetic resonance (CMR) vs. Baseline and echocardiographic characteristics model was evaluated on Major adverse cardiac events (MACE) (C-statistic 0.759, 95% CI 0.694-0.824, p=<0.001). Adding cardiac magnetic resonance data to baseline and echocardiographic models significantly improved the prediction of major adverse cardiac events in older STEMI patients (C-statistic 0.759 vs 0.685; P<0.001).
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