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June 25, 2019European Heart Journal - Cardiovascular ImagingOpen Access

Early or deferred cardiovascular magnetic resonance after ST-segment-elevation myocardial infarction for effective risk stratification

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Why the study?

Although CMR holds potential to improve risk stratification beyond the TIMI risk score in STEMI, the optimal timing for CMR after STEMI remains poorly defined.

Does the timing of CMR (early, deferred, or paired) after STEMI affect its prognostic performance for predicting death and HF hospitalization?

Population

492 reperfused STEMI patients

Comparison

Early-CMR vs deferred-CMR vs paired-CMRs stratification strategies

Design

Prospective registry-based study

Follow-up

Median 8.3 years

Authors

Pier Giorgio MasciPier Giorgio MasciCardiac ImagingAPAnna Giulia PavonCardiac ImagingGPGianluca PontoneUniversity of Foggia

Discussion

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Implication

CMR timing after STEMI appears interchangeable for prognosis; hypothesis-generating and should not yet alter practice.

Structured PICO

Does the timing of CMR (early, deferred, or paired) after STEMI affect its prognostic performance for predicting death and HF hospitalization?

P
Population
492 reperfused ST-segment-elevation myocardial infarction (STEMI) patients
I
Intervention
Prognostic stratification using early post-STEMI cardiovascular magnetic resonance (CMR) (median 4 days), deferred CMR (median 4.8 months), or paired CMRs
C
Comparator
Comparison among the three CMR timing stratification models
O
Outcome
Composite of all-death and heart failure (HF) hospitalizationcomposite

Early, deferred, or paired CMR strategies provide equivalent prognostic value for predicting death and heart failure hospitalization in reperfused STEMI patients.

Cite This Study

Masci et al. (2019) studied this question.

synapsesocial.com/papers/6a7d4cc0d85f1805a31cd7c9https://doi.org/10.1093/ehjci/jez179

Topics

STEMI managementPercutaneous coronary interventionCardiac MRI
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Application of the TIMI Risk Score for ST-Elevation MI in the National Registry of Myocardial Infarction 32001 · 271 citations
  2. 2Dynamic Edematous Response of the Human Heart to Myocardial Infarction2017 · 131 citations
  3. 3Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance2016 · 77 citations
  4. 4Acute Myocardial Infarction: Serial Cardiac MR Imaging Shows a Decrease in Delayed Enhancement of the Myocardium during the 1st Week after Reperfusion2009 · 115 citations
  5. 52017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation2017 · 9,930 citations