Key result
An 8-week exercise training regimen improved insulin-stimulated glucose disposal and increased the vasodilatory response to acetylcholine in overweight and type 2 diabetic subjects (P<0.05).
Why the study?
Does an 8-week exercise training regimen improve vasodilatory function and insulin sensitivity in overweight, insulin-resistant subjects and type 2 diabetic patients?
Population
Overweight, insulin-resistant subjects and type 2 diabetic patients, along with a lean, healthy, untrained…
Comparison
8-week exercise training regimen vs Pre-training baseline and lean, healthy…
Design
Cohort
Follow-up
8 weeks
Authors
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May support exercise to enhance endothelial function and insulin sensitivity; hypothesis-generating, requiring randomized confirmation before practice change.
Observational
Does an 8-week exercise training regimen improve vasodilatory function and insulin sensitivity in overweight, insulin-resistant subjects and type 2 diabetic patients?
p-value: p=<0.05
An 8-week aerobic exercise training regimen improves both endothelium-dependent vasodilation and insulin sensitivity in overweight and type 2 diabetic patients.
Filippis et al. (2006) conducted an observational in Overweight, insulin resistance, and type 2 diabetes mellitus. Exercise training regimen vs. Lean, healthy, untrained nonexercised controls was evaluated on Insulin sensitivity and vasodilatory function (p=<0.05). An 8-week exercise training regimen improved insulin-stimulated glucose disposal and increased the vasodilatory response to acetylcholine in overweight and type 2 diabetic subjects (P<0.05).
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