Key result
In patients with asymptomatic isolated distal deep vein thrombosis managed without anticoagulant therapy, there were zero cases of venous thromboembolism recurrence during a 1-year follow-up.
Why the study?
The natural history of asymptomatic isolated distal deep vein thrombosis of the leg is unclear.
Cohort (n=127)
No
Asymptomatic isolated distal DVT of the leg has a benign clinical course with a very low risk of symptomatic VTE or proximal extension even without anticoagulant therapy.
Answers are grounded in this paper and cite their sources.
Supports conservative management of asymptomatic isolated distal DVT; leaves open need for randomized confirmation.
Background: The natural history of asymptomatic isolated distal deep vein thrombosis (DVT) of the leg is unclear. This study aimed to describe a 3-month and 1-year clinical course after diagnosis of asymptomatic isolated distal DVT of the leg.
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Shimabukuro et al. (2019) conducted a cohort in Asymptomatic isolated distal deep vein thrombosis (n=127). Observation (no anticoagulant therapy) was evaluated on Venous thromboembolism recurrence. In patients with asymptomatic isolated distal deep vein thrombosis managed without anticoagulant therapy, there were zero cases of venous thromboembolism recurrence during a 1-year follow-up.
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