Key result
Cardiac magnetic resonance imaging at a median 11.6 years after Kawasaki disease onset showed no significant differences in biventricular volumes or function compared to healthy controls.
Why the study?
Does a history of Kawasaki disease result in long-term biventricular dysfunction or myocardial fibrosis as assessed by cardiac magnetic resonance imaging compared to healthy controls?
Population
60 patients with a history of Kawasaki disease and 20 healthy control subjects aged 12 to 24 years.
Comparison
Cardiac magnetic resonance imaging to assess… vs Healthy control subjects.
Design
Case-control
Follow-up
median 11.6 years after KD onset
Authors
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Reassuring preserved biventricular function on late CMR after Kawasaki disease without ischemia; leaves open fibrosis detection and surveillance needs in higher-risk subgroups.
Observational (n=80)
Does a history of Kawasaki disease result in long-term biventricular dysfunction or myocardial fibrosis as assessed by cardiac magnetic resonance imaging compared to healthy controls?
Long-term follow-up using CMR shows no significant difference in cardiac function between Kawasaki disease patients and healthy controls, except in a subgroup with prior ischemic heart disease.
Tacke et al. (2012) conducted an observational in Kawasaki disease (n=80). Cardiac magnetic resonance imaging vs. Healthy control subjects was evaluated on Biventricular volumes, function, and myocardial fibrosis. Cardiac magnetic resonance imaging at a median 11.6 years after Kawasaki disease onset showed no significant differences in biventricular volumes or function compared to healthy controls.
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