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May 29, 2026Indian Journal of Pharmacology

SOME PHARMACOLOGICAL STUDIES ON MORlNDA LUCIDA

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Authors

SAS. O. AweOOO. A. OLAJIDEJAJ. O. Adeboye

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Overview

Randomized trial shows anti-inflammatory, analgesic, and antipyretic effects in animal models, suggesting therapeutic potential.

Key Points

  • To investigate the pharmacological properties of methanol extract and fractions of Morinda lucida in animal models.
  • Utilized carrageenan-induced rat paw oedema model for anti-inflammatory testing.
  • Conducted acetic acid-induced writhings and tail immersion tests for analgesic evaluation.
  • Induced pyrexia with lipopolysaccharide to assess antipyretic activity.
  • MLE reduced carrageenan-induced paw oedema significantly.
  • MLFX 5 (5 and 10 mg/kg) significantly reduced writhings (P<0.05) and elevated pain threshold.
  • MLFX 5 decreased lipopolysaccharide-induced hyperpyrexia; MLFX 2 did not exhibit similar effects.

Cite This Study

Awe et al. (1998) studied this question.

synapsesocial.com/papers/6a192dbbfab5b468c4416a19https://doi.org/10.4103/ijpha_1998301_38
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  3. 3Comprehensive Profiling of Antioxidant, Antidiabetic, and Cytotoxic Compounds from Morinda lucida Benth Using 1H-NMR- and UHPLC-Q Exactive Orbitrap MS-Based Metabolomics Combined with Molecular Networking and Molecular Docking2026
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