Why the study?
How do design factors and mechanical stresses affect the degeneration of porcine bioprosthetic valves?
Population
Porcine bioprosthetic valves (PBVs) evaluated via computer-based numerical models
Design
Review
Authors
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Does not support immediate design or selection changes; extends computational evidence on stent parameters to degeneration risk.
How do design factors and mechanical stresses affect the degeneration of porcine bioprosthetic valves?
Computer-based numerical models demonstrate that mechanical stresses contribute to porcine bioprosthetic valve degeneration, and design optimizations like increased stent flexibility can reduce these stresses.
Sabbah et al. (1989) studied this question.
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