What does this research mean for the field?

The calcium antagonist felodipine produces beneficial acute hemodynamic and metabolic effects in patients with congestive heart failure, including increased cardiac index, reduced systemic vascular resistance, and an improved myocardial oxygen supply-to-demand ratio. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

April 1, 1984HeartOpen Access

Acute haemodynamic and metabolic effects of felodipine in congestive heart failure.

View Full Paper

Ask AI

Bookmark

Why the study?

Does felodipine improve acute haemodynamic and metabolic parameters in patients with congestive heart failure?

Structured PICO

Does felodipine improve acute haemodynamic and metabolic parameters in patients with congestive heart failure?

Population

11 patients with congestive heart failure

Intervention

Felodipine

Outcome

Acute haemodynamic and metabolic effects (including cardiac index, systemic vascular resistance, and left ventricular end diastolic pressure)surrogate

Acute administration of felodipine improves haemodynamics and myocardial oxygen balance in patients with congestive heart failure, suggesting potential value as an afterload reducing agent.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Felodipine may improve acute hemodynamics in heart failure; hypothesis-generating case report requiring randomized confirmation.

Cite This Study

Timmis et al. (1984) studied this question.

synapsesocial.com/papers/6a199c580ef26ba216f64d97 https://doi.org/10.1136/hrt.51.4.445

Topics

Heart failure HFrEF treatment HFpEF management

View Full Paper

Ask AI

Bookmark

Acute haemodynamic and metabolic effects of felodipine in congestive heart failure.

Structured PICO

Discussion

Implication

Cite This Study

Topics

Acute haemodynamic and metabolic effects of felodipine in congestive heart failure.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider