Key result
The presence of coronary collateral circulation was not associated with in-hospital mortality compared to its absence (13.2% vs 11.1%, p=0.67) in patients with first acute anterior STEMI.
Why the study?
Does the presence of coronary collateral circulation improve in-hospital mortality in patients with first acute anterior STEMI undergoing primary PCI?
Observational (n=220)
Does the presence of coronary collateral circulation improve in-hospital mortality in patients with first acute anterior STEMI undergoing primary PCI?
In patients with first acute anterior STEMI undergoing primary PCI, the presence of coronary collateral circulation is not associated with in-hospital mortality, whereas age, time to PCI, and unsuccessful PCI are independent predictors.
Answers are grounded in this paper and cite their sources.
Coronary collaterals should not inform acute mortality risk stratification in anterior STEMI; leaves open their role in larger or longer-term cohorts.
Results: A total of 220 patients mean age was of 61.412.3 years with first acute Anterior STEMI undergoing p-PCI were included the study. 34% of patients had CCC. The present study consisted of 64 female (29%) and 156 male (71%) patients. There were no statistically significant differences in respect to demographic characteristics, risk factors of coronary artery disease, LVEF, KILLIP classes, time from symptomps onset to PCI, door to baloon time, preprocedural and postprocedural angiographic characteristics and clinical outcomes which included cardiogenic shock on admission, cardiogenic shock in-hospital, fatal ventricular arrhtymias, complet AV block, mechanical complications and in-hospital mortality between the groups. In a stepwise backward multivariable logistic regression model, the independent prognostic indicators for in-hospital mortality were age (odds ratio [OR] 1.08, 95% CI 1.07 to 1.26, p=0.03), Time from symptoms onset to PCI (odds ratio [OR] 1.6, 95% CI 1.06 to 2.59, p=0.04) and unsuccessful p-PCI (odds ratio [OR] 3.3, 95% CI 1.04 to 10.9, p=0.04). Conclusion: Presence of CCC was not associated with in-hospital mortality in patients presenting with first acute Anterior STEMI undergoing p-PCI within first 6th hours.
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Altıntaş et al. (2018) conducted an observational in First acute anterior STEMI (n=220). Presence of Coronary Collateral Circulation vs. Absence of Coronary Collateral Circulation was evaluated on In-hospital mortality (p=0.67). The presence of coronary collateral circulation was not associated with in-hospital mortality compared to its absence (13.2% vs 11.1%, p=0.67) in patients with first acute anterior STEMI.
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