Key result
Absent coronary collaterals to RCA linked to ~4-fold higher in-hospital death in inferior STEMI.
Why the study?
Does the presence of coronary collateral circulation reduce in-hospital death and complications in patients with inferior STEMI undergoing primary PCI?
Cohort (n=235)
Does the presence of coronary collateral circulation reduce in-hospital death and complications in patients with inferior STEMI undergoing primary PCI?
Answers are grounded in this paper and cite their sources.
The presence of coronary collateral circulation in patients with inferior STEMI undergoing primary PCI is associated with a significantly lower risk of in-hospital death and right ventricular complications.
Objectives. Coronary collateral circulation (CCC) may limit the size of right ventricular (RV) infarcts but does not fully explain the relationship between CCC and clinical adverse events in patients with inferior STEMI. In this study, it was aimed to assess the relationship between preintervention angiographic evidence of CCC and clinical outcomes in patients with inferior STEMI who have undergone percutaneous coronary intervention. Methods. A total of 235 inferior STEMI patients who presented within the first 12 hours from the symptom onset were included. CCC to the right coronary artery (RCA) before angioplasty were angiographically assessed, establishing two groups: 147 (63%) patients without CCC and 88 (37%) with CCC according to presence of CCC. Results. RV infarction, complete atrioventricular block, VT/VF, cardiogenic shock, and in-hospital death were noted less frequently in patients with CCC than in those without CCC. Absence of CCC to RCA was found to be the independent predictor for in-hospital death among them (odds ratio 4.0, 95% CI 1.8-12.6; p = 0.03). Conclusion. Presence of angiographically detectable CCC was associated with better in-hospital outcomes including RV infarction, complete AV block, cardiogenic shock, and VT/VF in patients with inferior STEMI.
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Yaylak et al. (2015) conducted a cohort in Inferior ST elevation myocardial infarction (STEMI) (n=235). Absence of coronary collateral circulation (CCC) vs. Presence of coronary collateral circulation (CCC) was evaluated on In-hospital death (OR 4.0, 95% CI 1.8-12.6, p=0.03). The absence of coronary collateral circulation to the right coronary artery was an independent predictor of in-hospital death in patients with inferior STEMI.
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