Why the study?
Does evening administration of quinapril improve 24-hour blood pressure control compared to morning administration in patients with hypertension?
Does evening administration of quinapril improve 24-hour blood pressure control compared to morning administration in patients with hypertension?
Evening administration of quinapril 20 mg provides more sustained 24-hour blood pressure control and ACE inhibition compared to morning administration in hypertensive patients.
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Evening quinapril dosing may be preferred for sustained 24-hour BP control; extends chronotherapy evidence from RCTs in hypertension.
Palatini et al. (1992) studied this question.
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