Why the study?
Does quinapril reduce diastolic blood pressure in patients with mild to moderate essential hypertension?
Population
270 patients with mild to moderate essential hypertension
Comparison
Quinapril 20, 40, 80 mg daily with forced dose… vs Placebo
Design
RCT, Double-blind
Follow-up
12 weeks
Authors
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Quinapril effectively lowers DBP in mild-moderate hypertension; confirms ACEI benefit with once- or twice-daily dosing.
Does quinapril reduce diastolic blood pressure in patients with mild to moderate essential hypertension?
Quinapril administered once or twice daily effectively reduces diastolic blood pressure and is well tolerated in patients with mild to moderate essential hypertension.
Derek Maclean (1989) studied this question.
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