Why the study?
Does certoparin reduce fatal pulmonary embolism and mortality compared to unfractionated heparin in surgical patients?
Does certoparin reduce fatal pulmonary embolism and mortality compared to unfractionated heparin in surgical patients?
Once-daily certoparin is as effective and safe as three-times daily unfractionated heparin in preventing fatal pulmonary embolism and death in surgical patients.
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Certoparin matches unfractionated heparin for preventing fatal pulmonary embolism in surgical patients; confirms prior surrogate-endpoint equivalence with autopsy-proven outcomes.
Wolf et al. (2005) studied this question.
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