Why the study?
Is there an association between depressive symptoms, insulin resistance, and the risk of diabetes in women at midlife?
Is there an association between depressive symptoms, insulin resistance, and the risk of diabetes in women at midlife?
The authors address comments on their study, noting that baseline overt diabetes was excluded, making it unlikely that insulin resistance causing depression explains their findings.
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Excluding baseline diabetes reduces reverse causation likelihood; leaves open depressive symptoms as a diabetes risk driver in midlife women.
Everson‐Rose et al. (2005) studied this question.
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