Why the study?
Various strategies for VT ablation have been described, but their impact on VF is largely unknown.
Does substrate-based VT ablation targeting LAVA reduce recurrent VF events in patients with structural heart disease and both VT and VF?
Population
21 patients with structural heart disease and both VT and VF, plus 21 matched controls
Comparison
Catheter ablation targeting LAVAs vs matched controls without ablation
Design
Retrospective 2-center study
Follow-up
6 months
Authors
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Substrate ablation may reduce VF recurrences in structural heart disease; leaves open need for randomized confirmation.
Does substrate-based VT ablation targeting LAVA reduce recurrent VF events in patients with structural heart disease and both VT and VF?
Substrate-guided VT ablation targeting LAVAs significantly reduces recurrent VF events in patients with structural heart disease, suggesting shared arrhythmogenic substrates.
Kitamura et al. (2019) studied this question.