Why the study?
Do genetic variants associated with NT-proBNP levels have a causal effect on mortality in patients with acute coronary syndrome?
Do genetic variants associated with NT-proBNP levels have a causal effect on mortality in patients with acute coronary syndrome?
Mendelian randomization suggests that NT-proBNP levels do not have a direct causal effect on mortality in patients with acute coronary syndrome.
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No causal NT-proBNP effect on ACS mortality supported; leaves open validation of alternative pathways in prospective studies.
Johansson et al. (2016) studied this question.
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