Why the study?
Does intravenous fenoldopam mesylate reduce blood pressure as effectively as sodium nitroprusside in patients with severe systemic hypertension?
Population
33 patients with severe systemic hypertension defined as a diastolic blood pressure (DBP) >= 120 mm Hg
Comparison
Intravenous fenoldopam mesylate starting at 0.1… vs Intravenous sodium nitroprusside starting at 0.5…
Design
RCT, Randomized, Single-blind
Follow-up
Acute (hours)
Authors
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Supports fenoldopam as an alternative for acute severe hypertension; confirms comparable efficacy to nitroprusside in this RCT.
Does intravenous fenoldopam mesylate reduce blood pressure as effectively as sodium nitroprusside in patients with severe systemic hypertension?
Intravenous fenoldopam mesylate demonstrates similar overall efficacy to sodium nitroprusside in the acute treatment of severe systemic hypertension.
Pilmer et al. (1993) studied this question.
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