Why the study?
Does phenotyping of macrophages with monoclonal antibodies in endomyocardial biopsies help assess the diagnosis of myocarditis in patients clinically suspected of having the disease?
Population
53 patients clinically indicated to suffer from myocarditis, mean age 41 ± 5 years, 38 male and 15 female.
Design
Cross-sectional
Authors
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Macrophage phenotyping in EMB may aid myocarditis staging; leaves open added diagnostic value over standard histology in suspected cases.
Does phenotyping of macrophages with monoclonal antibodies in endomyocardial biopsies help assess the diagnosis of myocarditis in patients clinically suspected of having the disease?
Phenotyping macrophage subpopulations in endomyocardial biopsies can identify different stages of inflammation, offering a sensitive approach to diagnosing myocarditis.
Mues et al. (1990) studied this question.
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