What does this research mean for the field?

In response to pressure overload and increased cardiac hypertrophy, the myocardium expresses a smaller proportion of the longer N2BA titin isoform and more N2B titin, leading to higher passive tension. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

May 19, 2003Cardiovascular Research

Titin isoform expression in normal and hypertensive myocardium

View Full Paper

Ask AI

Bookmark

Authors

CWChris WarrenUniversity of Wisconsin–Madison

Discussion

Member takes

Implication

May inform titin-related passive tension mechanisms in hypertensive rat models; leaves open relevance to human diastolic dysfunction.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Chris Warren (2003) studied this question.

synapsesocial.com/papers/6a1d41bb33e2df9c962f3477 https://doi.org/10.1016/s0008-6363(03)00328-6

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Titin isoform expression in normal and hypertensive myocardium

Discussion

Member takes

Implication

Key Points

Cite This Study

Topics

Titin isoform expression in normal and hypertensive myocardium

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Topics

Also Consider