Why the study?
Are plasma adiponectin and leptin concentrations associated with low-grade hs-CRP elevation in nondiabetic women?
Population
384 nondiabetic Japanese women, mean age 53.6+/-0.8 years, BMI 23.0+/-0.2 kg/m2
Design
Cross-sectional
Authors
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Supports inflammation-adiponectin link in nondiabetic women; hypothesis-generating, needs prospective confirmation before clinical relevance.
Are plasma adiponectin and leptin concentrations associated with low-grade hs-CRP elevation in nondiabetic women?
Low-grade chronic inflammation is associated with decreased plasma adiponectin in nondiabetic women, suggesting a link between inflammation, adipose tissue, and atherosclerosis.
Matsubara et al. (2003) studied this question.
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