Key result
Hypertensive diabetic patients had significantly lower mean systolic blood pressure (136.62 mmHg) compared to patients with hypertension alone (146.66 mmHg), but exhibited a higher prevalence of end-organ damage (57% vs 44%).
Why the study?
Hypertension is twice as common in diabetic patients as in non-diabetics, but the clinical profile, laboratory features, and end organ damage in hypertensive patients with versus without diabetes needed better understanding.
Does the coexistence of diabetes in hypertensive patients alter clinical and laboratory profiles and increase the prevalence of end-organ damage compared to hypertension alone?
Cross-Sectional (n=200)
No
Does the coexistence of diabetes in hypertensive patients alter clinical and laboratory profiles and increase the prevalence of end-organ damage compared to hypertension alone?
Absolute Event Rate: 136.62% vs 146.66%
p-value: p=<0.001
The coexistence of diabetes and hypertension is associated with a higher prevalence of end-organ damage and worse metabolic profiles compared to hypertension alone, highlighting the need for comprehensive metabolic screening.
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Higher end-organ damage despite lower SBP in hypertensive diabetics may warrant intensified monitoring; leaves open diabetes-specific vascular effects.
Bhate et al. (2022) conducted a cross-sectional in Hypertension and Type 2 Diabetes (n=200). Hypertension plus Diabetes vs. Hypertension alone was evaluated on Mean systolic blood pressure (mmHg) (p=<0.001). Hypertensive diabetic patients had significantly lower mean systolic blood pressure (136.62 mmHg) compared to patients with hypertension alone (146.66 mmHg), but exhibited a higher prevalence of end-organ damage (57% vs 44%).
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