Key result
Thrombus aspiration during primary percutaneous coronary intervention was associated with a significant reduction in longer term mortality (adjusted HR 0.69; 95% CI 0.48-0.96; P=0.028).
Why the study?
Does thrombus aspiration during primary percutaneous coronary intervention reduce mortality in patients with ST-segment elevation myocardial infarction?
Population
2,567 consecutive patients with ST-elevation myocardial infarction treated with primary percutaneous…
Comparison
Thrombus aspiration during primary percutaneous… vs Primary percutaneous coronary intervention…
Design
Cohort
Follow-up
mean 9.9 months
Authors
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May support selective use in short ischemic time STEMI; hypothesis-generating and requires randomized confirmation.
Cohort (n=2,567)
Does thrombus aspiration during primary percutaneous coronary intervention reduce mortality in patients with ST-segment elevation myocardial infarction?
Effect estimate: HR 0.69 (95% CI 0.48-0.96)
p-value: p=0.028
In a real-world cohort of STEMI patients, thrombus aspiration during primary PCI was associated with reduced in-hospital and long-term mortality, particularly in those with short ischemic times.
Noman et al. (2012) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=2,567). Thrombus aspiration (thrombectomy) vs. No thrombus aspiration was evaluated on Longer term mortality (HR 0.69, 95% CI 0.48-0.96, p=0.028). Thrombus aspiration during primary percutaneous coronary intervention was associated with a significant reduction in longer term mortality (adjusted HR 0.69; 95% CI 0.48-0.96; P=0.028).
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