Studies of Fat Lipolysis by Post-Heparin Human Plasma Lipoprotein Lipase and by Human Pancreatic Lipase

Many studies indicate that unsaturated fats may lower serum cholesterol whereas saturated fats of animal origin usually increase it. The mechanism of these differing actions is unexplained, however. It has also been demonstrated that alimentary lipemia is cleared largely by an enzymatic lipolytic mechanism in which heparin is involved (heparin lipoprotein lipase). In this paper differences in hydrolysis of saturated and unsaturated fats by the heparin lipolytic factor are studied.