Population
in vitro models and transfected BHK cells studying Classical swine fever virus and hepatitis C virus IRES…
Comparison
Constructs with varying lengths of viral coding… vs Homologous combinations and constructs with…
Design
Preclinical
Authors
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Should not change clinical practice; leaves open IRES structural targeting for antiviral research.
CSFV IRES activity is highly dependent on the single-strandedness of the region immediately downstream of the initiation codon, revealing parallels with prokaryotic translation initiation.
Fletcher et al. (2002) studied this question.
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