Key result
Excess weight in young adults was associated with decreased endothelial function (P<0.01), increased left ventricular mass index (P<0.05), and elevated sympathetic nervous activity (P<0.001).
Why the study?
Is excess weight associated with subclinical organ damage and increased sympathetic nervous activity in young adults?
Cross-Sectional (n=43)
Is excess weight associated with subclinical organ damage and increased sympathetic nervous activity in young adults?
Excess weight in young adults is associated with subclinical cardiovascular and renal alterations, which are closely linked to increased sympathetic nervous activity.
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Supports early CV risk evaluation in overweight young adults; leaves open causality and need for longitudinal confirmation.
Lambert et al. (2010) conducted a cross-sectional in Obesity-Induced Subclinical Organ Damage (n=43). Excess weight (overweight or obese) vs. Lean (BMI <25 kg/m2) was evaluated on Subclinical target organ damage (renal function, left ventricular structure/function, and endothelial function) and muscle sympathetic nervous activity. Excess weight in young adults was associated with decreased endothelial function (P<0.01), increased left ventricular mass index (P<0.05), and elevated sympathetic nervous activity (P<0.001).
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