Extracellular vesicles play a mechanistic role at the intersection of inflammatory processes and cardiovascular diseases, including atherosclerosis, ischemic heart disease, and heart failure.
Cardiovascular disease is a leading cause of death worldwide. The underlying mechanisms of most cardiovascular disorders involve innate and adaptive immune responses, and extracellular vesicles are implicated in both. In this review, we describe the mechanistic role of extracellular vesicles at the intersection of inflammatory processes and cardiovascular disease. Our discussion focuses on atherosclerosis, myocardial ischemia and ischemic heart disease, heart failure, aortic aneurysms, and valvular pathology.
Akhmerov et al. (Mon,) conducted a review in Cardiovascular disease. Extracellular vesicles was evaluated. Extracellular vesicles play a mechanistic role at the intersection of inflammatory processes and cardiovascular diseases, including atherosclerosis, ischemic heart disease, and heart failure.