Population
Mathematical model of the medullary respiratory oscillator composed of computer-simulated neurons
Comparison
Simulated vagal discharge and uniform… vs Absence of simulated vagal discharge
Design
Preclinical
Authors
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Validates computational models of respiratory control; leaves open translation to human CO2 responses or clinical applications.
A computer simulation of the medullary respiratory oscillator successfully mimics the physiological response to CO2 in intact and vagotomized animals.
Geman et al. (1976) studied this question.
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