Population
Rat central nervous system and adrenal gland tissue from freshly killed rats (n=4)
Design
Preclinical
Authors
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Suggests peripheral ANP may influence central fluid balance; leaves open human cardiovascular relevance.
ANP binding sites are discretely localized in the rat CNS, particularly in regions outside the blood-brain barrier, suggesting peripheral ANP may regulate central control of salt and water balance.
Gibson et al. (1986) studied this question.
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