Why the study?
Does rapid ventricular pacing prevent ventricular arrhythmias during a subsequent coronary artery occlusion in anaesthetised dogs?
Population
25 chloralose-urethane anaesthetised mongrel dogs in a restricted body weight range
Comparison
Two 2-minute periods of rapid ventricular pacing… vs No preocclusion pacing (control)
Design
Preclinical
Follow-up
25 minutes
Authors
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Promising arrhythmia suppression by preocclusion pacing in dogs; hypothesis-generating and should not yet change practice.
Does rapid ventricular pacing prevent ventricular arrhythmias during a subsequent coronary artery occlusion in anaesthetised dogs?
Rapid ventricular pacing preconditions the myocardium and protects against the arrhythmogenic effects of prolonged coronary artery occlusion in a canine model.
Végh et al. (1991) studied this question.
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