Key result
Electrical or chemical stimulation of afferent cardiac sympathetic nerve fibers evoked reflex increases in myocardial contractility (dP/dt max) mediated entirely by the spinal cord.
Why the study?
Does electrical or chemical stimulation of afferent cardiac sympathetic nerve fibers elicit reflex changes in myocardial contractility in vagotomized cats and dogs?
Does electrical or chemical stimulation of afferent cardiac sympathetic nerve fibers elicit reflex changes in myocardial contractility in vagotomized cats and dogs?
This study provides the first demonstration of a cardiocardiac reflex mediated entirely by the spinal cord that increases myocardial contractility.
Authors
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Identifies spinal cardiocardiac reflex increasing contractility in animals; hypothesis-generating for human autonomic therapies.
Malliani et al. (1972) studied this question. Electrical stimulation of afferent cardiac sympathetic nerve fibers or chemical stimulation (veratridine) was evaluated on Changes in myocardial contractility (dP/dt max). Electrical or chemical stimulation of afferent cardiac sympathetic nerve fibers evoked reflex increases in myocardial contractility (dP/dt max) mediated entirely by the spinal cord.
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